ArtNr |
ABC-AP22225a-ev |
Hersteller |
Abcepta
|
Menge |
50 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
MYPT1, PPP1R12A, MBS, Myosin phosphatase target subunit 1, Protein phosphatase 1 regulatory subunit 12A, Myosin phosphatase-targeting subunit 1, Protein phosphatase myosin-binding subunit |
Lieferbar |
|
Primary Accession |
O14974 |
Antigen Type |
Synthesized Peptide |
Application |
WB |
Bio Background |
Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity. |
Bio References |
Takahashi N., et al.Genomics 44:150-152(1997).Guo J.H., et al.Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.Xia D., et al.Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.Ota T., et al.Nat. Genet. 36:40-45(2004).Scherer S.E., et al.Nature 440:346-351(2006). |
Clonality |
polyclonal |
Clone/Animal Names |
RB56565 |
Gene ID |
4659 |
Gene Name |
|
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, M, Rat |
Legend image 1 |
All lanes : Anti-MYPT Antibody at 1:2000 dilutionLane 1: 293 whole cell lysateLane 2: C2C12 whole cell lysateLane 3: C6 whole cell lysateLane 4: Hela whole cell lysateLane 5: HT-29 whole cell lysateLane 6: MCF-7 whole cell lysateLysates/proteins at 20 µg per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 115 kDaBlocking/Dilution buffer: 5% NFDM/TBST. |
Type image 1 |
WB |
Dilution image 1 |
1:2000 |
Other Accession |
Q90623; Q6DRG7; Q9DBR7; Q10728 |
Predicted |
C, Zf |
Isotype |
Rabbit Ig |
Calculated MW |
115281 |
Antigen Source |
HUMAN |
Target/Specificity |
This MYPT1 (Thr696) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 669-702 amino acids from the human MYPT1. |
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