ArtNr |
ABC-AP21729a-ev |
Hersteller |
Abcepta
|
Menge |
50 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
TMPRSS11D, HAT, Transmembrane protease serine 11D, Airway trypsin-like protease, Transmembrane protease serine 11D catalytic chain, 3421-, Transmembrane protease serine 11D non-catalytic chain |
Lieferbar |
|
Primary Accession |
O60235 |
Application |
WB |
Bio Background |
May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. Plays a role in the proteolytic processing of ACE2. Proteolytically cleaves and activates the human coronavirus 229E (HCoV-229E) spike glycoprotein which facilitate virus-cell membrane fusions; spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence. |
Bio References |
Yamaoka K., et al.J. Biol. Chem. 273:11895-11901(1998).Yasuoka S., et al.Am. J. Respir. Cell Mol. Biol. 16:300-308(1997).Bertram S., et al.J. Virol. 87:6150-6160(2013).Heurich A., et al.J. Virol. 88:1293-1307(2014). |
Clonality |
polyclonal |
Clone/Animal Names |
RB53576 |
Gene ID |
9407 |
Gene Name |
TMPRSS11D |
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
All lanes : Anti-TMPRSS11D Antibody (N-Term) at 1:2000 dilutionLane 1: human liver lysateLane 2: HepG2 whole cell lysateLysates/proteins at 20 µg per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 46 kDaBlocking/Dilution buffer: 5% NFDM/TBST. |
Type image 1 |
WB |
Dilution image 1 |
1:2000 |
Isotype |
Rabbit Ig |
Calculated MW |
46263 |
Antigen Source |
HUMAN |
Target/Specificity |
This TMPRSS11D antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 84-119 amino acids from human TMPRSS11D. |
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