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TSG101 Antibody (C-term)

TSG101 Antibody (C-term)

ArtNr	ABC-AP2155b-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	TSG101, Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101
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Primary Accession	Q99816
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	TSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
Bio References	Favre, M., et al., J. Acquir. Immune Defic. Syndr. 34(2):127-133 (2003). Lu, Q., et al., Proc. Natl. Acad. Sci. U.S.A. 100(13):7626-7631 (2003). Goila-Gaur, R., et al., J. Virol. 77(11):6507-6519 (2003). Blanco, S., et al., FEMS Microbiol. Lett. 221(2):151-154 (2003). Martin-Serrano, J., et al., J. Virol. 77(8):4794-4804 (2003).
Clonality	Polyclonal
Clone/Animal Names	RB4377
Gene ID	7251
Gene Name	TSG101
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	The anti-TSG101 Pab (Cat. #AP2155b) is used in Western blot to detect TSG101 in ZR75-1 cell lysate
Type image 1	WB
Dilution image 1	1:1000
Other Accession	Q6IRE4; Q61187; NP_006283
Predicted	M, Rat
Isotype	Rabbit Ig
Calculated MW	43944
Antigen Region	340-370
Antigen Source	HUMAN
Target/Specificity	This TSG101 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 340-370 amino acids from the C-terminal region of human TSG101.
NCBI Accession	NP_006283.1

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ABC-AP2155b-ev-datasheet.pdf

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Menge: 80 ul

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Lieferung vsl. bis 08.11.2024

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