ArtNr |
ABC-AP21071a |
Hersteller |
Abcepta
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB |
Specific against |
other |
Host |
Rabbit |
Isotype |
Ig |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
ZO1, TJP1, Tight junction protein ZO-1, Tight junction protein 1, Zona occludens protein 1, Zonula occludens protein 1 |
Lieferbar |
|
Primary Accession |
Q07157 |
Application |
WB |
Bio Background |
The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells. |
Bio References |
Willott E., et al.Proc. Natl. Acad. Sci. U.S.A. 90:7834-7838(1993).Ota T., et al.Nat. Genet. 36:40-45(2004).Zody M.C., et al.Nature 440:671-675(2006).Cohen C.J., et al.Proc. Natl. Acad. Sci. U.S.A. 98:15191-15196(2001).D'Atri F., et al.J. Biol. Chem. 277:27757-27764(2002). |
Clonality |
Polyclonal |
Clone/Animal Names |
RB51788 |
Gene ID |
7082 |
Gene Name |
TJP1 |
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Western blot analysis of lysate from A431 cell line, using TJP1 Antibody (Cterm)(Cat. #AP21071a). AP21071a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Western blot analysis of lysate from A431 cell line, using TJP1 Antibody (Cterm)(Cat. #AP21071a). AP21071a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug. |
Type image 2 |
WB |
Dilution image 2 |
1:1000 |
Isotype |
Rabbit Ig |
Calculated MW |
195459 |
Antigen Source |
HUMAN |
Target/Specificity |
This TJP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1328-1362 amino acids from the C-terminal region of human TJP1. |
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