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(Mouse) Sox17 Antibody (C-term)

(Mouse) Sox17 Antibody (C-term)

ArtNr	ABC-AP20861c-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Sox17, Transcription factor SOX-17, Sox-17
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Primary Accession	Q61473
Application	WB
Bio Background	Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells. Isoform 2 (T-SOX17) shows no DNA-binding activity.
Bio References	Kanai Y., et al.J. Cell Biol. 133:667-681(1996). Carninci P., et al.Science 309:1559-1563(2005). Layfield R., et al.Submitted (FEB-1994) to the EMBL/GenBank/DDBJ databases. Kanai-Azuma M., et al.Development 129:2367-2379(2002). Kim I., et al.Cell 130:470-483(2007).
Clonality	Polyclonal
Clone/Animal Names	RB51152
Gene ID	20671
Gene Name	Sox17
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Western blot analysis of lysates from LNCaP, mouse F9 cell line (from left to right), using Sox17 Antibody (C-term)(Cat. #AP20861c). AP20861c was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
Type image 1	WB
Dilution image 1	1:1000
Isotype	Rabbit Ig
Calculated MW	44646
Antigen Source	HUMAN
Target/Specificity	This (Mouse) Sox17 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 376-409 amino acids from the C-terminal region of human (Mouse) Sox17.

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Menge: 80 ul

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