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RRM1 Antibody (N-term)

RRM1 Antibody (N-term)

ArtNr	ABC-AP20081a-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	RRM1, RR1, Ribonucleoside-diphosphate reductase large subunit, Ribonucleoside-diphosphate reductase subunit M1, Ribonucleotide reductase large subunit
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Primary Accession	P23921
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.
Bio References	Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010) Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010) Vinolas, N., et al. Lung Cancer (2010) In press : Niida, H., et al. Genes Dev. 24(4):333-338(2010) Dong, S., et al. J Hematol Oncol 3, 10 (2010) :
Clonality	Polyclonal
Clone/Animal Names	RB42407
Gene ID	6240
Gene Name	RRM1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	RRM1 Antibody (N-term) (Cat. #AP20081a) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RRM1 antibody detected the RRM1 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Other Accession	P07742; NP_001024.1
Predicted	M
Isotype	Rabbit Ig
Calculated MW	90070
Antigen Region	71-100
Antigen Source	HUMAN
Target/Specificity	This RRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-100 amino acids from the N-terminal region of human RRM1.
NCBI Accession	NP_001024.1

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ABC-AP20081a-ev-datasheet.pdf

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Menge: 80 ul

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Lieferung vsl. bis 04.10.2024

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