Alias |
Nuclear factor erythroid 2-related factor 3, NF-E2-related factor 3, NFE2-related factor 3, Nuclear factor, erythroid derived 2, like 3, NFE2L3, NRF3 |
Bio Background |
This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18. |
Bio References |
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Davila, S., et al. Genes Immun. 11(3):232-238(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Zhang, Y., et al. J. Biol. Chem. 284(5):3195-3210(2009) |