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NMD3 Antibody (C-term)

NMD3 Antibody (C-term)

ArtNr	ABC-AP1948b
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	NMD3, 60S ribosomal export protein NMD3, hNMD3
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Primary Accession	Q96D46
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	It has been suggested that NMD3 is a cytoplasmic factor required for a late cytoplasmic assembly step of the 60S subunit but is not a ribosomal protein. A mutation in NMD3 was found to be lethal in the absence of XRN1, which encodes the major cytoplasmic exoribonuclease responsible for mRNA turnover. The NMD3 protein sequence does not contain readily recognizable motifs of known function. However, NMD3 orthologues display an amino-terminal domain containing four repeats of Cx2C, reminiscent of zinc-binding proteins, implicated in nucleic acid binding or protein oligomerization.
Bio References	Trotta, C.R., et al., EMBO J. 22(11):2841-2851 (2003). Ho, J.H. et al., Mol. Cell. Bio., 19(3):2389-2399 (1999).
Clonality	Polyclonal
Clone/Animal Names	RB9708
Gene ID	51068
Gene Name	NMD3
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Western blot analysis of anti-NMD3 Pab (Cat. #AP1948b) in mouse heart (left) and T47D (right)tissue lysates (35ug/lane). NMD3(arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Isotype	Rabbit Ig
Calculated MW	57603
Antigen Region	410-440
Antigen Source	HUMAN
Target/Specificity	This NMD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-440 amino acids from the C-terminal region of human NMD3.
NCBI Accession	NP_057022.2

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ABC-AP1948b-datasheet.pdf

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Menge: 400 ul

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