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SF3B4 Antibody(Center)

SF3B4 Antibody(Center)

ArtNr	ABC-AP19396c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	SF3B4, SAP49, Splicing factor 3B subunit 4, Pre-mRNA-splicing factor SF3b 49 kDa subunit, SF3b50, Spliceosome-associated protein 49, SAP 49
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Primary Accession	Q15427
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
Bio References	Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008) Rikova, K., et al. Cell 131(6):1190-1203(2007) Watanabe, H., et al. J. Biol. Chem. 282(28):20728-20738(2007) Wu, C., et al. Proteomics 7(11):1775-1785(2007) Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Clonality	Polyclonal
Clone/Animal Names	RB40410
Gene ID	10262
Gene Name	SF3B4
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	SF3B4 Antibody (Center)(Cat. #AP19396c) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SF3B4 antibody detected the SF3B4 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Other Accession	Q6AYL5; Q8QZY9; NP_005841.1
Predicted	M, Rat
Isotype	Rabbit Ig
Calculated MW	44386
Antigen Region	158-187
Antigen Source	HUMAN
Target/Specificity	This SF3B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158-187 amino acids from the Central region of human SF3B4.
NCBI Accession	NP_005841.1

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ABC-AP19396c-datasheet.pdf

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Menge: 400 ul

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