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Mouse Khdrbs1 Antibody (C-term)

ArtNr ABC-AP19343b-ev
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen WB
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products KH domain-containing, RNA-binding, signal transduction-associated protein 1, GAP-associated tyrosine phosphoprotein p62, Src-associated in mitosis 68 kDa protein, p21 Ras GTPase-activating protein-associated p62, p68, Sam68, Khdrbs1 {ECO:0000312|MGI:MGI:893579}
Lieferbar
Primary Accession
Q60749
Antigen Type
Synthetic Peptide
Application
WB
Bio Background
Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.
Bio References
Sette, C., et al. J. Androl. 31(1):66-74(2010)
Maroni, P., et al. Mol. Cell. Endocrinol. 309 (1-2), 26-31 (2009) :
Paronetto, M.P., et al. J. Cell Biol. 185(2):235-249(2009)
Huot, M.E., et al. Mol. Cell. Biol. 29(7):1933-1943(2009)
Rajan, P., et al. BMC Cell Biol. 10, 82 (2009) :
Clonality
Polyclonal
Clone/Animal Names
RB40286
Gene ID
20218
Gene Name
Khdrbs1 {ECO:0000312|MGI:MGI:893579}
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
M
Legend image 1
Mouse Khdrbs1 Antibody (C-term)(Cat. #AP19343b) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Khdrbs1 antibody detected the Khdrbs1 protein (arrow).
Type image 1
WB
Dilution image 1
1:1000
Other Accession
Q91V33; Q07666; Q8UUW7; NP_035447.3
Predicted
C, H, Rat
Isotype
Rabbit Ig
Calculated MW
48371
Antigen Region
414-443
Antigen Source
MOUSE
Target/Specificity
This Mouse Khdrbs1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-443 amino acids from the C-terminal region of mouse Khdrbs1.
NCBI Accession
NP_035447.3

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 80 ul
Lieferbar: In stock
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