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Mouse Cbx5 Antibody (C-term)

Mouse Cbx5 Antibody (C-term)

ArtNr	ABC-AP19229b-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Chromobox protein homolog 5, Heterochromatin protein 1 homolog alpha, Cbx5, Hp1a, HP1 alpha
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Primary Accession	Q61686
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins (By similarity).
Bio References	Sun, Y., et al. Biophys. J. 99(4):1274-1283(2010) Muller, K.P., et al. Biophys. J. 97(11):2876-2885(2009) Dong, K.B., et al. EMBO J. 27(20):2691-2701(2008) Villeneuve, L.M., et al. Proc. Natl. Acad. Sci. U.S.A. 105(26):9047-9052(2008) Brancorsini, S., et al. Cell Cycle 7(10):1415-1422(2008)
Clonality	Polyclonal
Clone/Animal Names	RB40179
Gene ID	12419
Gene Name	Cbx5
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	M
Legend image 1	Mouse Cbx5 Antibody (C-term) (Cat. #AP19229b) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the Cbx5 antibody detected the Cbx5 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Other Accession	P45973; NP_001070257.1
Predicted	H
Isotype	Rabbit Ig
Calculated MW	22186
Antigen Region	160-186
Antigen Source	MOUSE
Target/Specificity	This Mouse Cbx5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-186 amino acids from the C-terminal region of mouse Cbx5.
NCBI Accession	NP_001070257.1; NP_001103686.1; NP_031652.1

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ABC-AP19229b-ev-datasheet.pdf

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Menge: 80 ul

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Lieferung vsl. bis 06.09.2024

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