ArtNr |
ABC-AP19190a-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
BEST3, VMD2L3, Bestrophin-3, Vitelliform macular dystrophy 2-like protein 3 |
Lieferbar |
|
Primary Accession |
Q8N1M1 |
Antigen Type |
Synthetic Peptide |
Application |
WB |
Bio Background |
BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliformmacular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins aretransmembrane (TM) proteins that share a homology region containinga high content of aromatic residues, including an invariantarg-phe-pro (RFP) motif. The bestrophin genes share a conservedgene structure, with almost identical sizes of the 8 RFP-TMdomain-encoding exons and highly conserved exon-intron boundaries.Each of the 4 bestrophin genes has a unique 3-prime end of variablelength (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]). |
Bio References |
Marsey, L.L., et al. J. Physiol. (Lond.) 587 (PT 10), 2211-2224 (2009) :Qu, Z.Q., et al. J. Biol. Chem. 282(24):17460-17467(2007)Tsunenari, T., et al. J. Biol. Chem. 278(42):41114-41125(2003)Stohr, H., et al. Eur. J. Hum. Genet. 10(4):281-284(2002)Marquardt, A., et al. Hum. Mol. Genet. 7(9):1517-1525(1998) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB39849 |
Gene ID |
144453 |
Gene Name |
BEST3 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
BEST3 Antibody (N-term) (Cat. #AP19190a) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the BEST3 antibody detected the BEST3 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Other Accession |
NP_116124.2 |
Isotype |
Rabbit Ig |
Calculated MW |
76107 |
Antigen Region |
40-68 |
Antigen Source |
HUMAN |
Target/Specificity |
This BEST3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the N-terminal region of human BEST3. |
NCBI Accession |
NP_116124.2; NP_689652.2 |
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