DUSP13 Antibody (C-term)

Synthetic Peptide

Members of the protein-tyrosine phosphatase superfamily
cooperate with protein kinases to regulate cell proliferation and
differentiation. This superfamily is separated into two families
based on the substrate that is dephosphorylated. One family, the
dual specificity phosphatases (DSPs) acts on both phosphotyrosine
and phosphoserine/threonine residues. This gene encodes different
but related DSP proteins through the use of non-overlapping open
reading frames, alternate splicing, and presumed different
transcription promoters. Expression of the distinct proteins from
this gene has been found to be tissue specific and the proteins may
be involved in postnatal development of specific tissues. A protein
encoded by the upstream ORF was found in skeletal muscle, whereas
the encoded protein from the downstream ORF was found only in
testis. In mouse, a similar pattern of expression was found.
Multiple alternatively spliced transcript variants were described,
but the full-length sequence of only some were determined.

Polyclonal

51207

Affinity Purified Rabbit Polyclonal Antibody (Pab)

DUSP13 Antibody (C-term)(Cat. #AP18781b) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the DUSP13 antibody detected the DUSP13 protein (arrow).

1:1000

Rabbit Ig

147-173

This DUSP13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-173 amino acids from the C-terminal region of human DUSP13.