HOXD8 Antibody (C-term)

Synthetic Peptide

This gene belongs to the homeobox family of genes. The
homeobox genes encode a highly conserved family of transcription
factors that play an important role in morphogenesis in all
multicellular organisms. Mammals possess four similar homeobox gene
clusters, HOXA, HOXB, HOXC and HOXD, located on different
chromosomes, consisting of 9 to 11 genes arranged in tandem. This
gene is one of several homeobox HOXD genes located in a cluster on
chromosome 2. Deletions that remove the entire HOXD gene cluster or
the 5' end of this cluster have been associated with severe limb
and genital abnormalities. In addition to effects during
embryogenesis, this particular gene may also play a role in adult
urogenital tract function.

Polyclonal

3234

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Fluorescent image of HUVEC cell stained with HOXD8 Antibody (C-term)(Cat#AP18731b).HUVEC cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with HOXD8 primary antibody (1:25, 1 h at 37℃). For secondary antibody, Alexa Fluor® 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37℃).Cytoplasmic actin was counterstained with Alexa Fluor® 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37℃).HOXD8 immunoreactivity is localized to Nucleus significantly.

1:10~50

WB

NP_062458.1

31911

HUMAN

NP_001186675.1; NP_062458.1