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ATG9A Antibody

ATG9A Antibody

ArtNr	ABC-AP1814i-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	ATG9A, APG9L1, Autophagy-related protein 9A, APG9-like 1, mATG9
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Primary Accession	Q7Z3C6
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	Apg9 plays a direct role in the formation of the cytoplasm to vacuole targeting and autophagic vesicles, possibly serving as a marker for a specialized compartment essential for these vesicle-mediated alternative targeting pathways. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole).
Bio References	Baehrecke EH. Nat Rev Mol Cell Biol. 6(6):505-10. (2005) Lum JJ, et al. Nat Rev Mol Cell Biol. 6(6):439-48. (2005) Greenberg JT. Dev Cell. 8(6):799-801. (2005) Levine B. Cell. 120(2):159-62. (2005) Shintani T and Klionsky DJ. Science. 306(5698):990-5. (2004)
Clonality	Polyclonal
Clone/Animal Names	RB13941
Gene ID	79065
Gene Name	ATG9A
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	All lanes : Anti-APG9L1 Antibody (S738) at 1:1000 dilution Lane 1: MCF-7 whole cell lysate Lane 2: HepG2 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 94kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with APG9L1 Antibody (S738) (Cat.#AP1814i), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	Q5FWU3; Q3T904
Predicted	B, Rat
Isotype	Rabbit Ig
Calculated MW	94447
Antigen Region	723-753
Antigen Source	HUMAN
Target/Specificity	This ATG9A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 723~753 amino acids surrounding S738 of human APG9L1.
NCBI Accession	NP_001070666.1; NP_076990.4

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