ASB7 Antibody (Center)

Q91ZU0; Q9BGT9; NP_078984.2

The protein encoded by this gene belongs to a family of
ankyrin repeat proteins that, along with four other protein
families, contains a C-terminal SOCS box motif. Growing evidence
suggests that the SOCS box acts as a bridge between specific
substrate-binding domains and the more generic proteins that
comprise a large family of E3 ubiquitin protein ligases. In this
way, SOCS box containing proteins may regulate protein turnover by
targeting proteins for polyubiquination and, therefore, for
proteasome-mediated degradation. Two alternative transcripts
encoding different isoforms have been described. [provided by
RefSeq].

140460

H

36011

HUMAN

NP_078984.2; NP_937886.1