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LPXN Antibody (Center)

LPXN Antibody (Center)

ArtNr	ABC-AP17801c-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	LPXN, LDLP, Leupaxin
Lieferbar
Primary Accession	O60711
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Bio References	Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Tanaka, T., et al. Cancer Sci. 101(2):363-368(2010) Dai, H.P., et al. Genes Chromosomes Cancer 48(12):1027-1036(2009) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Sundberg-Smith, L.J., et al. Circ. Res. 102(12):1502-1511(2008)
Clonality	Polyclonal
Clone/Animal Names	RB37022
Gene ID	9404
Gene Name	LPXN
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	LPXN Antibody (Center) (Cat. #AP17801c) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the LPXN antibody detected the LPXN protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Western blot analysis of LPXN (arrow) using rabbit polyclonal LPXN Antibody (Center) (Cat. #AP17801c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the LPXN gene.
Type image 2	WB
Dilution image 2	1:1000
Other Accession	Q99N69; NP_004802.1
Isotype	Rabbit Ig
Calculated MW	43332
Antigen Region	229-257
Antigen Source	HUMAN
Target/Specificity	This LPXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-257 amino acids from the Central region of human LPXN.
NCBI Accession	NP_001137467.1; NP_004802.1

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Menge: 80 ul

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