ArtNr |
ABC-AP17565C-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB, IF |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
HOXC10, Homeobox protein Hox-C10, HOX3I, Homeobox protein Hox-3I |
Lieferbar |
|
Primary Accession |
Q9NYD6 |
Antigen Type |
Synthetic Peptide |
Application |
IF, WB |
Bio Background |
This gene belongs to the homeobox family of genes. Thehomeobox genes encode a highly conserved family of transcriptionfactors that play an important role in morphogenesis in allmulticellular organisms. Mammals possess four similar homeobox geneclusters, HOXA, HOXB, HOXC and HOXD, which are located on differentchromosomes and consist of 9 to 11 genes arranged in tandem. Thisgene is one of several homeobox HOXC genes located in a cluster onchromosome 12. The protein level is controlled during celldifferentiation and proliferation, which may indicate this proteinhas a role in origin activation. |
Bio References |
Hwang, J.H., et al. Cloning Stem Cells 11(2):269-279(2009)Zhai, Y., et al. Cancer Res. 67(21):10163-10172(2007)Gabellini, D., et al. EMBO J. 22(14):3715-3724(2003)Kosaki, K., et al. Teratology 65(2):50-62(2002)Sandrock, B., et al. J. Biol. Chem. 276(38):35328-35333(2001) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB37164 |
Gene ID |
3226 |
Gene Name |
HOXC10 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Fluorescent confocal image of MCF-7 cell stained with HOXC10 Antibody (Center)(Cat#AP17565c).MCF-7 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with HOXC10 primary antibody (1:25, 1 h at 37℃). For secondary antibody, Alexa Fluor® 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37℃).Cytoplasmic actin was counterstained with Alexa Fluor® 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37℃). Nuclei were counterstained with DAPI (blue) (10 µg/ml, 10 min). HOXC10 immunoreactivity is localized to Nucleus significantly. |
Type image 1 |
IF |
Dilution image 1 |
1:10~50 |
Legend image 2 |
HOXC10 Antibody (Center) (Cat. #AP17565c) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the HOXC10 antibody detected the HOXC10 protein (arrow). |
Type image 2 |
WB |
Dilution image 2 |
1:1000 |
Other Accession |
NP_059105.2 |
Isotype |
Rabbit Ig |
Calculated MW |
38073 |
Antigen Region |
152-179 |
Antigen Source |
HUMAN |
Target/Specificity |
This HOXC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-179 amino acids from the Central region of human HOXC10. |
NCBI Accession |
NP_059105.2 |
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