KCNN1 Antibody (C-term)

NP_002239.2

Action potentials in vertebrate neurons are followed by an
afterhyperpolarization (AHP) that may persist for several seconds
and may have profound consequences for the firing pattern of the
neuron. Each component of the AHP is kinetically distinct and is
mediated by different calcium-activated potassium channels. The
protein encoded by this gene is activated before membrane
hyperpolarization and is thought to regulate neuronal excitability
by contributing to the slow component of synaptic AHP. The encoded
protein is an integral membrane protein that forms a
voltage-independent calcium-activated channel with three other
calmodulin-binding subunits. This gene is a member of the KCNN
family of potassium channel genes.

3780

H

391-419

This KCNN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids from the C-terminal region of human KCNN1.