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IQCB1 Antibody (Center)

ArtNr ABC-AP17066C
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen WB
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products IQCB1, KIAA0036, NPHP5, IQ calmodulin-binding motif-containing protein 1, Nephrocystin-5, p53 and DNA damage-regulated IQ motif protein, PIQ
Lieferbar
Primary Accession
Q15051
Antigen Type
Synthetic Peptide
Application
WB
Bio Background
This gene encodes a nephrocystin protein that interacts
with calmodulin and the retinitis pigmentosa GTPase regulator
protein. The encoded protein has a central coiled-coil region and
two calmodulin-binding IQ domains. It is localized to the primary
cilia of renal epithelial cells and connecting cilia of
photoreceptor cells. The protein is thought to play a role in
ciliary function. Defects in this gene result in Senior-Loken
syndrome type 5. Alternative splicing results in multiple
transcript variants.
Bio References
Hildebrandt, F., et al. J. Am. Soc. Nephrol. 20(1):23-35(2009)
Schafer, T., et al. Hum. Mol. Genet. 17(23):3655-3662(2008)
Luo, X., et al. Cancer Res. 65(23):10725-10733(2005)
le Maire, A., et al. Proteins 59(2):347-355(2005)
Mollet, G., et al. Hum. Mol. Genet. 14(5):645-656(2005)
Clonality
Polyclonal
Clone/Animal Names
RB36926
Gene ID
9657
Gene Name
IQCB1
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
IQCB1 Antibody (Center) (Cat. #AP17066c) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the IQCB1 antibody detected the IQCB1 protein (arrow).
Type image 1
WB
Dilution image 1
1:1000
Other Accession
NP_001018865.2; NP_001018864.2
Isotype
Rabbit Ig
Calculated MW
68929
Antigen Region
384-411
Antigen Source
HUMAN
Target/Specificity
This IQCB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-411 amino acids from the Central region of human IQCB1.
NCBI Accession
NP_001018864.2; NP_001018865.2

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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