ArtNr |
ABC-AP17066C |
Hersteller |
Abcepta
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB |
Specific against |
other |
Host |
Rabbit |
Isotype |
Ig |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
IQCB1, KIAA0036, NPHP5, IQ calmodulin-binding motif-containing protein 1, Nephrocystin-5, p53 and DNA damage-regulated IQ motif protein, PIQ |
Lieferbar |
|
Primary Accession |
Q15051 |
Antigen Type |
Synthetic Peptide |
Application |
WB |
Bio Background |
This gene encodes a nephrocystin protein that interactswith calmodulin and the retinitis pigmentosa GTPase regulatorprotein. The encoded protein has a central coiled-coil region andtwo calmodulin-binding IQ domains. It is localized to the primarycilia of renal epithelial cells and connecting cilia ofphotoreceptor cells. The protein is thought to play a role inciliary function. Defects in this gene result in Senior-Lokensyndrome type 5. Alternative splicing results in multipletranscript variants. |
Bio References |
Hildebrandt, F., et al. J. Am. Soc. Nephrol. 20(1):23-35(2009)Schafer, T., et al. Hum. Mol. Genet. 17(23):3655-3662(2008)Luo, X., et al. Cancer Res. 65(23):10725-10733(2005)le Maire, A., et al. Proteins 59(2):347-355(2005)Mollet, G., et al. Hum. Mol. Genet. 14(5):645-656(2005) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB36926 |
Gene ID |
9657 |
Gene Name |
IQCB1 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
IQCB1 Antibody (Center) (Cat. #AP17066c) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the IQCB1 antibody detected the IQCB1 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Other Accession |
NP_001018865.2; NP_001018864.2 |
Isotype |
Rabbit Ig |
Calculated MW |
68929 |
Antigen Region |
384-411 |
Antigen Source |
HUMAN |
Target/Specificity |
This IQCB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-411 amino acids from the Central region of human IQCB1. |
NCBI Accession |
NP_001018864.2; NP_001018865.2 |
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