ArtNr |
ABC-AP17057a-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
DHPS, DS, Deoxyhypusine synthase, DHS |
Lieferbar |
|
Primary Accession |
P49366 |
Antigen Type |
Synthetic Peptide |
Application |
WB |
Bio Background |
The unusual amino acid hypusine is formedposttranslationally and is only found in a single cellular protein, eukaryotic translation initiation factor 5A. In the first step ofhypusine biosynthesis, deoxyhypusine synthase catalyzes theNAD-dependent transfer of the butylamine moiety of spermidine tothe epsilon-amino group of a specific lysine residue of the EIF5Aprecursor protein to form the intermediate deoxyhypusine residue.This gene consists of nine exons spanning 6.6 kb. Three transcriptvariants have been isolated. However, only transcript variant 1encodes an active protein. The shorter variants may act asmodulating factors of DHPS activity. |
Bio References |
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)Alker, A.P., et al. Trop. Med. Int. Health 13(11):1384-1391(2008)Matsuoka, S., et al. Science 316(5828):1160-1166(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) : |
Clonality |
Polyclonal |
Clone/Animal Names |
RB36905 |
Gene ID |
1725 |
Gene Name |
DHPS |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
DHPS Antibody (N-term) (Cat. #AP17057a) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the DHPS antibody detected the DHPS protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Other Accession |
NP_001921.1; NP_037538.1 |
Isotype |
Rabbit Ig |
Calculated MW |
40971 |
Antigen Region |
16-43 |
Antigen Source |
HUMAN |
Target/Specificity |
This DHPS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-43 amino acids from the N-terminal region of human DHPS. |
NCBI Accession |
NP_001193903.1; NP_001921.1; NP_037538.1 |
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