Bio Background |
Poly(ADP-ribose) glycohydrolase (PARG) is the majorenzyme responsible for the catabolism of poly(ADP-ribose), areversible covalent-modifier of chromosomal proteins. The proteinis found in many tissues and may be subject to proteolysisgenerating smaller, active products. |
Bio References |
Whatcott, C.J., et al. Exp. Cell Res. 315(20):3477-3485(2009)Frizzell, K.M., et al. J. Biol. Chem. 284(49):33926-33938(2009)Erdelyi, K., et al. FASEB J. 23(10):3553-3563(2009)Ame, J.C., et al. J. Cell. Sci. 122 (PT 12), 1990-2002 (2009) :Uchiumi, F., et al. Genes Cells 13(12):1229-1247(2008) |