SF3B2 Antibody (Center)

Synthetic Peptide

This gene encodes subunit 2 of the splicing factor 3b
protein complex. Splicing factor 3b, together with splicing factor
3a and a 12S RNA unit, forms the U2 small nuclear
ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a
complex binds pre-mRNA upstream of the intron's branch site in a
sequence-independent manner and may anchor the U2 snRNP to the
pre-mRNA. Splicing factor 3b is also a component of the minor
U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream
of the branch site at the anchoring site. Subunit 2 also interacts
directly with subunit 4 of the splicing factor 3b complex. Subunit
2 is a highly hydrophilic protein with a proline-rich N-terminus
and a glutamate-rich stretch in the C-terminus. [provided by
RefSeq].

Polyclonal

10992

Affinity Purified Rabbit Polyclonal Antibody (Pab)

All lanes : Anti-SF3B2 Antibody (Center) at 1:2000 dilution
Lane 1: 293 whole cell lysate
Lane 2: A431 whole cell lysate
Lane 3: A549 whole cell lysate
Lane 4: Hela whole cell lysate
Lane 5: mouse spleen lysate
Lane 6: mouse testis lysate
Lane 7: rat lung lysate
Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 100 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

1:2000

Rabbit Ig

539-568

This SF3B2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 539-568 amino acids from the Central region of human SF3B2.