ArtNr |
ABC-AP16115b-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
SGCD, Delta-sarcoglycan, 35 kDa dystrophin-associated glycoprotein, 35DAG, Delta-SG |
Lieferbar |
|
Primary Accession |
Q92629 |
Antigen Type |
Synthetic Peptide |
Application |
WB |
Bio Background |
The protein encoded by this gene is one of the four knowncomponents of the sarcoglycan complex, which is a subcomplex of thedystrophin-glycoprotein complex (DGC). DGC forms a link between theF-actin cytoskeleton and the extracellular matrix. This protein isexpressed most abundantly in skeletal and cardiac muscle. Mutationsin this gene have been associated with autosomal recessivelimb-girdle muscular dystrophy and dilated cardiomyopathy.Alternatively spliced transcript variants encoding distinctisoforms have been observed for this gene. |
Bio References |
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Zimmerman, R.S., et al. Genet. Med. 12(5):268-278(2010)Ordonez-Razo, R.M., et al. Genet Test Mol Biomarkers 14(2):237-240(2010)Lin, W.Y., et al. BMC Res Notes 3, 26 (2010) : |
Clonality |
Polyclonal |
Clone/Animal Names |
RB35027 |
Gene ID |
6444 |
Gene Name |
SGCD |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
M |
Legend image 1 |
SGCD Antibody (C-term) (Cat. #AP16115b) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SGCD antibody detected the SGCD protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Other Accession |
NP_001121681.1; NP_000328.2; NP_758447.1 |
Isotype |
Rabbit Ig |
Calculated MW |
32071 |
Antigen Region |
232-261 |
Antigen Source |
HUMAN |
Target/Specificity |
This SGCD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-261 amino acids from the C-terminal region of human SGCD. |
NCBI Accession |
NP_000328.2; NP_001121681.1; NP_758447.1 |
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