Hersteller |
Abcepta
|
Kategorie |
|
Typ |
Antibody Primary |
Specific against |
other |
Isotype |
IgG |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB, IHC-P |
Menge |
200 ul |
Host |
Rabbit |
ArtNr |
ABC-AP1561a |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Primary Accession |
P62760 |
Antigen Type |
Synthetic Peptide |
Application |
WB, IHC-P |
Bio Background |
The visinin and visinin-like peptides represent a family of calcium-binding proteins that are highly expressed in the retina. Visinin has been shown to be a cone cell-specific protein with a molecular weight of 24 kDa. Several members of the visinin family of genes have been isolated and characterized from different species. These peptides are believed to be involved in the processes of phototransduction. The recoverin gene (RCV1) is believed to be involved in the pathophysiology of retinopathy in cancer patients. |
Bio References |
Braunewell, K.H., et al., Neuropharmacology 44(6):707-715 (2003). Lin, L., et al., J. Biol. Chem. 277(44):41872-41878 (2002). Spilker, C., et al., J. Neurosci. 22(17):7331-7339 (2002). Bernstein, H.G., et al., Neuroreport 13(4):393-396 (2002). Lin, L., et al., Biochem. Biophys. Res. Commun. 296(4):827-832 (2002). |
Clonality |
Polyclonal |
Clone/Animal Names |
RB0498 |
Gene ID |
7447 |
Gene Name |
VSNL1 |
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, M, Rat |
Legend image 1 |
Western blot analysis of lysates from SW480 cell line, human brain, mouse brain and rat brain tissue lysate(from left to right), using VILIP1 Antibody (C-term)(Cat. #AP1561a). AP1561a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Western blot analysis of lysates from human brain, mouse brain, rat brain and rat eyeball tissue lysate (from left to right), using VILIP1 Antibody (C-term)(Cat. #AP1561a). AP1561a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane. |
Type image 2 |
WB |
Dilution image 2 |
1:1000 |
Legend image 3 |
Formalin-fixed and paraffin-embedded human brain tissue reacted with VILIP1 antibody (C-term ), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Type image 3 |
IHC-P |
Dilution image 3 |
1:50~100 |
Legend image 4 |
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with VILIP1 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Type image 4 |
IHC-P |
Dilution image 4 |
1:50~100 |
Isotype |
Rabbit IgG |
Calculated MW |
22142 |
Antigen Region |
123-150 |
Antigen Source |
HUMAN |
Target/Specificity |
This VILIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-150 amino acids from the C-terminal region of human VILIP1. |
NCBI Accession |
NP_003376.2 |
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