ArtNr |
ABC-AP14832A |
Hersteller |
Abcepta
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
Isotype |
Ig |
ECLASS 5.1 |
32160702 |
ECLASS 6.1 |
32160702 |
ECLASS 8.0 |
32160702 |
ECLASS 9.0 |
32160702 |
ECLASS 10.0.1 |
32160702 |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
KCND2, KIAA1044, Potassium voltage-gated channel subfamily D member 2, Voltage-gated potassium channel subunit Kv42 |
Lieferbar |
|
Primary Accession |
Q9NZV8 |
Antigen Type |
Synthetic Peptide |
Application |
IHC-P, WB |
Bio Background |
Voltage-gated potassium (Kv) channels represent the mostcomplex class of voltage-gated ion channels from both functionaland structural standpoints. Their diverse functions includeregulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smoothmuscle contraction, and cell volume. Four sequence-relatedpotassium channel genes - shaker, shaw, shab, and shal - have beenidentified in Drosophila, and each has been shown to have humanhomolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which formvoltage-activated A-type potassium ion channels and are prominentin the repolarization phase of the action potential. This membermediates a rapidly inactivating, A-type outward potassium currentwhich is not under the control of the N terminus as it is in Shakerchannels. |
Bio References |
Foeger, N.C., et al. J. Biol. Chem. 285(43):33413-33422(2010)Levy, D.I., et al. J. Physiol. (Lond.) 588 (PT 14), 2657-2668 (2010) :Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Aronica, E., et al. Neurobiol. Dis. 36(1):81-95(2009)Tayo, B.O., et al. Circ Cardiovasc Genet 2(1):38-45(2009) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB34603 |
Gene ID |
3751 |
Gene Name |
KCND2 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
KCND2 Antibody (N-term) (Cat. #AP14832a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the KCND2 antibody detected the KCND2 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
KCND2 Antibody (N-term) (AP14832a)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KCND2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:10~50 |
Other Accession |
Q63881; P59995; Q9Z0V2; NP_036413.1 |
Predicted |
M, Rb, Rat |
Isotype |
Rabbit Ig |
Calculated MW |
70537 |
Antigen Region |
123-151 |
Antigen Source |
HUMAN |
Target/Specificity |
This KCND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-151 amino acids from the N-terminal region of human KCND2. |
NCBI Accession |
NP_036413.1 |
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