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PLD2 Antibody (N-term)

PLD2 Antibody (N-term)

ArtNr	ABC-AP14669a-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PLD2, Phospholipase D2, Choline phosphatase 2, PLD1C, Phosphatidylcholine-hydrolyzing phospholipase D2, hPLD2, PLD 2
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Primary Accession	O14939
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.[supplied by OMIM].
Bio References	Chae, Y.C., et al. Mol. Cell. Biol. 30(21):5086-5098(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Knapek, K., et al. Mol. Cell. Biol. 30(18):4492-4506(2010) Tabatabaian, F., et al. J. Biol. Chem. 285(25):18991-19001(2010) Kang, D.W., et al. PLoS ONE 5 (8), E12109 (2010) :
Clonality	Polyclonal
Clone/Animal Names	RB34393
Gene ID	5338
Gene Name	PLD2 (HGNC:9068)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	PLD2 Antibody (N-term) (Cat. #AP14669a) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the PLD2 antibody detected the PLD2 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	PLD2 Antibody (N-term) (Cat. #AP14669a) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the PLD2 antibody detected the PLD2 protein (arrow).
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Western blot analysis of lysate from human heart tissue lysate, using PLD2 Antibody (N-term)(Cat. #AP14669a). AP14669a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.
Type image 3	WB
Dilution image 3	1:1000
Legend image 4	Anti-PLD2 Antibody (N-term) at 1:2000 dilution + Mouse lung tissue lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 106 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 4	WB
Dilution image 4	1:2000
Other Accession	Q0V8L6; NP_002654.3
Predicted	B
Isotype	Rabbit IgG
Calculated MW	105987
Antigen Region	10-39
Antigen Source	HUMAN
Target/Specificity	This PLD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human PLD2.
NCBI Accession	NP_001230037.1; NP_002654.3

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Menge: 80 ul

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