ArtNr |
ABC-AP14669a-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
PLD2, Phospholipase D2, Choline phosphatase 2, PLD1C, Phosphatidylcholine-hydrolyzing phospholipase D2, hPLD2, PLD 2 |
Lieferbar |
|
Primary Accession |
O14939 |
Antigen Type |
Synthetic Peptide |
Application |
WB |
Bio Background |
Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidicacid and choline. Activation of PC-specific PLDs occurs as aconsequence of agonist stimulation of both tyrosine kinase and Gprotein-coupled receptors. PC-specific PLDs have been proposed tofunction in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.[supplied byOMIM]. |
Bio References |
Chae, Y.C., et al. Mol. Cell. Biol. 30(21):5086-5098(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Knapek, K., et al. Mol. Cell. Biol. 30(18):4492-4506(2010)Tabatabaian, F., et al. J. Biol. Chem. 285(25):18991-19001(2010)Kang, D.W., et al. PLoS ONE 5 (8), E12109 (2010) : |
Clonality |
Polyclonal |
Clone/Animal Names |
RB34393 |
Gene ID |
5338 |
Gene Name |
|
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, M |
Legend image 1 |
PLD2 Antibody (N-term) (Cat. #AP14669a) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the PLD2 antibody detected the PLD2 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
PLD2 Antibody (N-term) (Cat. #AP14669a) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the PLD2 antibody detected the PLD2 protein (arrow). |
Type image 2 |
WB |
Dilution image 2 |
1:1000 |
Legend image 3 |
Western blot analysis of lysate from human heart tissue lysate, using PLD2 Antibody (N-term)(Cat. #AP14669a). AP14669a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug. |
Type image 3 |
WB |
Dilution image 3 |
1:1000 |
Legend image 4 |
Anti-PLD2 Antibody (N-term) at 1:2000 dilution + Mouse lung tissue lysateLysates/proteins at 20 µg per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 106 kDaBlocking/Dilution buffer: 5% NFDM/TBST. |
Type image 4 |
WB |
Dilution image 4 |
1:2000 |
Other Accession |
Q0V8L6; NP_002654.3 |
Predicted |
B |
Isotype |
Rabbit IgG |
Calculated MW |
105987 |
Antigen Region |
10-39 |
Antigen Source |
HUMAN |
Target/Specificity |
This PLD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human PLD2. |
NCBI Accession |
NP_001230037.1; NP_002654.3 |
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