ArtNr |
ABC-AP14462a |
Hersteller |
Abcepta
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
Isotype |
Ig |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
AKAP82, A-kinase anchor protein 4, A-kinase anchor protein 82 kDa, Major sperm fibrous sheath protein, Protein kinase A-anchoring protein 4, HI, hAKAP82, PRKA4, AKAP-4, AKAP 82, AKAP4 (HGNC:374) |
Lieferbar |
|
Primary Accession |
Q5JQC9 |
Antigen Type |
Synthetic Peptide |
Application |
IHC-P, WB |
Bio Background |
The A-kinase anchor proteins (AKAPs) are a group ofstructurally diverse proteins, which have the common function ofbinding to the regulatory subunit of protein kinase A (PKA) andconfining the holoenzyme to discrete locations within the cell.This gene encodes a member of the AKAP family. The encoded proteinis localized to the sperm flagellum and may be involved in theregulation of sperm motility. Alternative splicing of this generesults in two transcript variants encoding different isoforms. |
Bio References |
Moretti, E., et al. Asian J. Androl. 9(5):641-649(2007)Lefievre, L., et al. Proteomics 7(17):3066-3084(2007)Ross, M.T., et al. Nature 434(7031):325-337(2005)Brown, P.R., et al. Biol. Reprod. 68(6):2241-2248(2003)Ficarro, S., et al. J. Biol. Chem. 278(13):11579-11589(2003) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB35105 |
Gene ID |
8852 |
Gene Name |
|
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
AKAP4 Antibody (N-term) (Cat. #AP14462a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the AKAP4 antibody detected the AKAP4 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
AKAP4 Antibody (N-term) (AP14462a)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AKAP4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:10~50 |
Other Accession |
NP_003877.2; NP_647450.1 |
Isotype |
Rabbit Ig |
Calculated MW |
94477 |
Antigen Region |
10-36 |
Antigen Source |
HUMAN |
Target/Specificity |
This AKAP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-36 amino acids from the N-terminal region of human AKAP4. |
NCBI Accession |
NP_003877.2; NP_647450.1 |
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