ArtNr |
ABC-AP14364c |
Hersteller |
Abcepta
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
Isotype |
Ig |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
IL9R, Interleukin-9 receptor, CD129, IL-9R, IL-9 receptor |
Lieferbar |
|
Primary Accession |
Q01113 |
Antigen Type |
Synthetic Peptide |
Application |
WB, IHC-P |
Bio Background |
The protein encoded by this gene is a cytokine receptorthat specifically mediates the biological effects of interleukin 9(IL9). The functional IL9 receptor complex requires this protein aswell as the interleukin 2 receptor, gamma (IL2RG), a common gammasubunit shared by the receptors of many different cytokines. Theligand binding of this receptor leads to the activation of variousJAK kinases and STAT proteins, which connect to different biologicresponses. This gene is located at the pseudoautosomal regions of Xand Y chromosomes. Genetic studies suggested an association of thisgene with the development of asthma. Multiple pseudogenes onchromosome 9, 10, 16, and 18 have been described. Alternativelyspliced transcript variants have been found for this gene. |
Bio References |
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :McCanlies, E.C., et al. J. Occup. Environ. Med. 52(7):680-684(2010)Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) : |
Clonality |
Polyclonal |
Clone/Animal Names |
RB34191 |
Gene ID |
3581 |
Gene Name |
IL9R |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Anti-IL9R Antibody (Center) at 1:1000 dilution + Jurkat whole cell lysateLysates/proteins at 20 µg per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 57 kDaBlocking/Dilution buffer: 5% NFDM/TBST. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
IL9R Antibody (Center) (AP14364c)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IL9R Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:10~50 |
Other Accession |
NP_002177.2 |
Isotype |
Rabbit Ig |
Calculated MW |
57147 |
Antigen Region |
170-199 |
Antigen Source |
HUMAN |
Target/Specificity |
This IL9R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-199 amino acids from the Central region of human IL9R. |
NCBI Accession |
NP_002177.2; NP_789743.2 |
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