HNRNPM Antibody (N-term)

Synthetic Peptide

This gene belongs to the subfamily of ubiquitously
expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The
hnRNPs are RNA binding proteins and they complex with heterogeneous
nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs
in the nucleus and appear to influence pre-mRNA processing and
other aspects of mRNA metabolism and transport. While all of the
hnRNPs are present in the nucleus, some seem to shuttle between the
nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic
acid binding properties. The protein encoded by this gene has three
repeats of quasi-RRM domains that bind to RNAs. This protein also
constitutes a monomer of the N-acetylglucosamine-specific receptor
which is postulated to trigger selective recycling of immature
GlcNAc-bearing thyroglobulin molecules. Multiple alternatively
spliced transcript variants are known for this gene but only two
transcripts has been isolated.

Polyclonal

4670

Affinity Purified Rabbit Polyclonal Antibody (Pab)

HNRNPM Antibody (N-term) (Cat. #AP14009a) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the HNRNPM antibody detected the HNRNPM protein (arrow).

1:1000

IHC-P

NP_112480.2; NP_005959.2

77516

HUMAN

NP_005959.2; NP_112480.2