TRAF3 Antibody (C-term)

Synthetic Peptide

The protein encoded by this gene is a member of the TNF
receptor associated factor (TRAF) protein family. TRAF proteins
associate with, and mediate the signal transduction from, members
of the TNF receptor (TNFR) superfamily. This protein participates
in the signal transduction of CD40, a TNFR family member important
for the activation of the immune response. This protein is found to
be a critical component of the lymphotoxin-beta receptor (LTbetaR)
signaling complex, which induces NF-kappaB activation and cell
death initiated by LTbeta ligation. Epstein-Barr virus encoded
latent infection membrane protein-1 (LMP1) can interact with this
and several other members of the TRAF family, which may be
essential for the oncogenic effects of LMP1. Three alternatively
spliced transcript variants encoding two distinct isoforms have
been reported.

Polyclonal

7187

Affinity Purified Rabbit Polyclonal Antibody (Pab)

TRAF3 Antibody (C-term) (Cat. #AP13945b) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the TRAF3 antibody detected the TRAF3 protein (arrow).

1:1000

WB

Q60803; NP_663777.1; NP_663778.1; NP_003291.2

64490

HUMAN

NP_001186356.1; NP_003291.2; NP_663777.1; NP_663778.1