ArtNr |
ABC-AP13905b |
Hersteller |
Abcepta
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
Isotype |
Ig |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
AP2A1, ADTAA, CLAPA1, AP-2 complex subunit alpha-1, 100 kDa coated vesicle protein A, Adaptor protein complex AP-2 subunit alpha-1, Alpha-adaptin A, Alpha1-adaptin, Clathrin assembly protein complex 2 alpha-A large chain, Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit, Adaptor-related protein complex 2 subunit alpha-1 |
Lieferbar |
|
Primary Accession |
O95782 |
Antigen Type |
Synthetic Peptide |
Application |
IHC-P, WB |
Bio Background |
This gene encodes the alpha 1 adaptin subunit of theadaptor protein 2 (AP-2) complex found in clathrin coated vesicles.The AP-2 complex is a heterotetramer consisting of two largeadaptins (alpha or beta), a medium adaptin (mu), and a smalladaptin (sigma). The complex is part of the protein coat on thecytoplasmic face of coated vesicles which links clathrin toreceptors in vesicles. Alternative splicing of this gene results intwo transcript variants encoding two different isoforms. A thirdtranscript variant has been described, but its full length naturehas not been determined. |
Bio References |
Mitchell, R.S., et al. J. Virol. 82(16):7758-7767(2008)Kitagawa, Y., et al. Virology 373(1):171-180(2008)Stove, V., et al. J. Virol. 79(17):11422-11433(2005)Lu, W., et al. Neuron 47(3):407-421(2005)Pope, S.N., et al. J. Steroid Biochem. Mol. Biol. 94 (1-3), 203-208 (2005) : |
Clonality |
Polyclonal |
Clone/Animal Names |
RB34053 |
Gene ID |
160 |
Gene Name |
AP2A1 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
AP2A1 Antibody (C-term) (Cat. #AP13905b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the AP2A1 antibody detected the AP2A1 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
AP2A1 Antibody (C-term) (AP13905b)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AP2A1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:10~50 |
Other Accession |
P17426; NP_570603.2; NP_055018.2 |
Predicted |
M |
Isotype |
Rabbit Ig |
Calculated MW |
107546 |
Antigen Region |
706-735 |
Antigen Source |
HUMAN |
Target/Specificity |
This AP2A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 706-735 amino acids from the C-terminal region of human AP2A1. |
NCBI Accession |
NP_055018.2; NP_570603.2 |
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