ArtNr |
ABC-AP13737b-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB, IF, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
IL-13, IL13, NC30, Interleukin-13 |
Lieferbar |
|
Primary Accession |
P35225 |
Antigen Type |
Synthetic Peptide |
Application |
IHC-P, IF, WB |
Bio Background |
This gene encodes an immunoregulatory cytokine producedprimarily by activated Th2 cells. This cytokine is involved inseveral stages of B-cell maturation and differentiation. Itup-regulates CD23 and MHC class II expression, and promotes IgEisotype switching of B cells. This cytokine down-regulatesmacrophage activity, thereby inhibits the production ofpro-inflammatory cytokines and chemokines. This cytokine is foundto be critical to the pathogenesis of allergen-induced asthma butoperates through mechanisms independent of IgE and eosinophils.This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster onchromosome 5q, with this gene particularly close to IL4. [providedby RefSeq]. |
Bio References |
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Shi, X., et al. Anat Rec (Hoboken) 293(9):1470-1476(2010)Beckers, M.M., et al. Eur. J. Intern. Med. 21(4):289-292(2010)Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press :Zhao, M., et al. J. Biomed. Biotechnol. 2010, 931018 (2010) : |
Clonality |
Polyclonal |
Clone/Animal Names |
RB33718 |
Gene ID |
3596 |
Gene Name |
IL13 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Confocal immunofluorescent analysis of IL13 Antibody (C-term) (Cat#AP13737b) with NCI-H460 cell line followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). |
Type image 1 |
IF |
Dilution image 1 |
1:10~50 |
Legend image 2 |
IL13 Antibody (C-term) (Cat. #AP13737b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the IL13 antibody detected the IL13 protein (arrow). |
Type image 2 |
WB |
Dilution image 2 |
1:1000 |
Legend image 3 |
IL13 Antibody (C-term) (AP13737b)immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IL13 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Type image 3 |
IHC-P |
Dilution image 3 |
1:10~50 |
Other Accession |
NP_002179.2 |
Isotype |
Rabbit Ig |
Calculated MW |
15816 |
Antigen Region |
118-146 |
Antigen Source |
HUMAN |
Target/Specificity |
This IL13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-146 amino acids from the C-terminal region of human IL13. |
NCBI Accession |
NP_002179.2 |
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