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SMC1A Antibody (N-term)

SMC1A Antibody (N-term)

ArtNr	ABC-AP13544a-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	SMC1, SMC1A, DXS423E, KIAA0178, SMC1L1, Structural maintenance of chromosomes protein 1A, SMC protein 1A, SMC-1-alpha, SMC-1A, Sb18, SB18
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Primary Accession	Q14683
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. [provided by RefSeq].
Bio References	Limongelli, G., et al. Am. J. Med. Genet. A 152A (8), 2127-2129 (2010) : Homme, C., et al. Oncol. Rep. 24(1):47-56(2010) Pie, J., et al. Am. J. Med. Genet. A 152A (4), 924-929 (2010) : Wong, R.W. Cell Cycle 9(1):198-200(2010) Liu, J., et al. Hum. Mutat. 30(11):1535-1542(2009)
Clonality	Polyclonal
Clone/Animal Names	RB33672
Gene ID	8243
Gene Name	SMC1A
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	SMC1A Antibody (N-term) (Cat. #AP13544a) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the SMC1A antibody detected the SMC1A protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Other Accession	Q9CU62; O97593; NP_006297.2
Predicted	B, M
Isotype	Rabbit Ig
Calculated MW	143233
Antigen Region	307-336
Antigen Source	HUMAN
Target/Specificity	This SMC1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-336 amino acids from the N-terminal region of human SMC1A.
NCBI Accession	NP_006297.2

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ABC-AP13544a-ev-datasheet.pdf

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Menge: 80 ul

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