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SGEF Antibody (Center)

SGEF Antibody (Center)

ArtNr	ABC-AP13325c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	SGEF, ARHGEF26, Rho guanine nucleotide exchange factor 26, SH3 domain-containing guanine exchange factor
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Primary Accession	Q96DR7
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	SGEF activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.
Bio References	Yamada, S., et al. Oncogene 23(35):5901-5911(2004) Ellerbroek, S.M., et al. Mol. Biol. Cell 15(7):3309-3319(2004) Qi, H., et al. Endocrinology 144(5):1742-1752(2003)
Clonality	Polyclonal
Clone/Animal Names	RB33350
Gene ID	26084
Gene Name	ARHGEF26
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	SGEF Antibody (Center) (Cat. #AP13325c) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SGEF antibody detected the SGEF protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	SGEF Antibody (Center) (Cat. #AP13325c)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SGEF Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	NP_056410.3
Isotype	Rabbit Ig
Calculated MW	97346
Antigen Region	378-406
Antigen Source	HUMAN
Target/Specificity	This SGEF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the Central region of human SGEF.
NCBI Accession	NP_001238891.1; NP_001238892.1; NP_056410.3

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ABC-AP13325c-datasheet.pdf

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Menge: 400 ul

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