ArtNr |
ABC-AP12801a-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
STARD4, StAR-related lipid transfer protein 4, START domain-containing protein 4, StARD4 |
Lieferbar |
|
Primary Accession |
Q96DR4 |
Antigen Type |
Synthetic Peptide |
Application |
IHC-P, WB |
Bio Background |
Cholesterol homeostasis is regulated, at least in part, bysterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM184756) and by liver X receptors (e.g., LXRA; MIM 602423). Uponsterol depletion, LXRs are inactive and SREBPs are cleaved, afterwhich they bind promoter SREs and activate genes involved incholesterol biosynthesis and uptake. Sterol transport is mediatedby vesicles or by soluble protein carriers, such as steroidogenicacute regulatory protein (STAR; MIM 600617). STAR is homologous toa family of proteins containing a 200- to 210-amino acidSTAR-related lipid transfer (START) domain, including STARD4(Soccio et al., 2002 [PubMed 12011452]). |
Bio References |
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Korytowski, W., et al. Biochem. Biophys. Res. Commun. 392(1):58-62(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Rodriguez-Agudo, D., et al. J. Lipid Res. 49(7):1409-1419(2008) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB32027 |
Gene ID |
134429 |
Gene Name |
STARD4 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
STARD4 Antibody (N-term) (Cat. #AP12801a) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the STARD4 antibody detected the STARD4 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
STARD4 Antibody (N-term) (Cat. #AP12801a)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STARD4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:10~50 |
Other Accession |
NP_631903.1 |
Isotype |
Rabbit Ig |
Calculated MW |
23517 |
Antigen Region |
8-37 |
Antigen Source |
HUMAN |
Target/Specificity |
This STARD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-37 amino acids from the N-terminal region of human STARD4. |
NCBI Accession |
NP_631903.1 |
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