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STARD4 Antibody (N-term)

STARD4 Antibody (N-term)

ArtNr	ABC-AP12801a-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	STARD4, StAR-related lipid transfer protein 4, START domain-containing protein 4, StARD4
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Primary Accession	Q96DR4
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).
Bio References	Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Korytowski, W., et al. Biochem. Biophys. Res. Commun. 392(1):58-62(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Rodriguez-Agudo, D., et al. J. Lipid Res. 49(7):1409-1419(2008)
Clonality	Polyclonal
Clone/Animal Names	RB32027
Gene ID	134429
Gene Name	STARD4
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	STARD4 Antibody (N-term) (Cat. #AP12801a) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the STARD4 antibody detected the STARD4 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	STARD4 Antibody (N-term) (Cat. #AP12801a)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STARD4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	NP_631903.1
Isotype	Rabbit Ig
Calculated MW	23517
Antigen Region	8-37
Antigen Source	HUMAN
Target/Specificity	This STARD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-37 amino acids from the N-terminal region of human STARD4.
NCBI Accession	NP_631903.1

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ABC-AP12801a-ev-datasheet.pdf

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Menge: 80 ul

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