HIST3H3 Antibody (Center)

Synthetic Peptide

Histones are basic nuclear proteins that are responsible
for the nucleosome structure of the chromosomal fiber in
eukaryotes. Nucleosomes consist of approximately 146 bp of DNA
wrapped around a histone octamer composed of pairs of each of the
four core histones (H2A, H2B, H3, and H4). The chromatin fiber is
further compacted through the interaction of a linker histone, H1,
with the DNA between the nucleosomes to form higher order chromatin
structures. This gene is intronless and encodes a member of the
histone H3 family. Transcripts from this gene lack polyA tails;
instead, they contain a palindromic termination element. This gene
is located separately from the other H3 genes that are in the
histone gene cluster on chromosome 6p22-p21.3. [provided by
RefSeq].

Polyclonal

8290

Affinity Purified Rabbit Polyclonal Antibody (Pab)

HIST3H3 Antibody (Center) (Cat. #AP12225c) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the HIST3H3 antibody detected the HIST3H3 protein (arrow).

1:1000

FC

NP_003484.1

15508

HUMAN

NP_003484.1