Vergleich

CYP5A1 Antibody (Center)

Hersteller Abcepta
Kategorie
Typ Antibody Primary
Specific against other
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen WB, IHC-P
Menge 80 ul
Host Rabbit
ArtNr ABC-AP12077c-ev
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Primary Accession
P24557
Antigen Type
Synthetic Peptide
Application
IHC-P, WB
Bio Background
This gene encodes a member of the cytochrome P450
superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases which catalyze many reactions involved in drug
metabolism and synthesis of cholesterol, steroids and other lipids.
However, this protein is considered a member of the cytochrome P450
superfamily on the basis of sequence similarity rather than
functional similarity. This endoplasmic reticulum membrane protein
catalyzes the conversion of prostglandin H2 to thromboxane A2, a
potent vasoconstrictor and inducer of platelet aggregation. The
enzyme plays a role in several pathophysiological processes
including hemostasis, cardiovascular disease, and stroke.
Alternatively spliced transcript variants encoding different
isoforms have been found for this gene.
Bio References
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Wang, L.H., et al. Prostaglandins Other Lipid Mediat. 68-69, 409-422 (2002) :
Tazawa, R., et al. Arch. Biochem. Biophys. 334(2):349-356(1996)
Baek, S.J., et al. Gene 173(2):251-256(1996)
Wang, L.H., et al. Arch. Biochem. Biophys. 315(2):273-278(1994)
Clonality
Polyclonal
Clone/Animal Names
RB17080
Gene ID
6916
Gene Name
TBXAS1
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
M
Legend image 1
CYP5A1 Antibody (Center) (Cat. #AP12077c) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the CYP5A1 antibody detected the CYP5A1 protein (arrow).
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
CYP5A1 Antibody (Center) (Cat. #AP12077c)immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CYP5A1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2
IHC-P
Dilution image 2
1:10~50
Other Accession
Q2PG45; Q2KIG5; NP_001052.2; NP_001124438.1
Predicted
B, Pr
Isotype
Rabbit Ig
Calculated MW
60518
Antigen Region
226-257
Antigen Source
HUMAN
Target/Specificity
This CYP5A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-257 amino acids from the Central region of human CYP5A1.
NCBI Accession
NP_001052.2; NP_001124438.1; NP_001159726.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 80 ul
Lieferbar: In stock
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