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DDIT3 Antibody (C-term A135)

DDIT3 Antibody (C-term A135)

ArtNr	ABC-AP11955B-ev-80ul
Hersteller	Abcepta
Menge	80 ul
Kategorie	Oncology Antibodies Hematology Leukemia Sarcoma Flow Cytometry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	Immunofluorescence, Western Blot, Flow cytometry
Clon	1773CT634.49.61
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DNA damage-inducible transcript 3 protein, DDIT-3, C/EBP zeta, C/EBP-homologous protein, CHOP, C/EBP-homologous protein 10, CHOP-10, CCAAT/enhancer-binding protein homologous protein, Growth arrest and DNA damage-inducible protein GADD153, DDIT3, CHOP, CH
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Primary Accession	P35638
Other Accession	P35639; P14607; Q0IIB6; NP_004074
Antigen Type	Synthetic Peptide
Bio Background	This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
Bio References	Park, S.H., et al. J. Immunol. 185(9):5522-5530(2010) Goodall, J.C., et al. Proc. Natl. Acad. Sci. U.S.A. 107(41):17698-17703(2010) Zhang, H.M., et al. J. Virol. 84(17):8446-8459(2010) Cazanave, S.C., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 299 (1), G236-G243 (2010) : Wang, Y.L., et al. J. Exp. Clin. Cancer Res. 29, 54 (2010) :
Gene ID	1649
Gene Name	DDIT3
Reactivity	H, M
Predicted	B, Ha
Calculated MW	19175
Antigen Region	120-149
Antigen Source	HUMAN
Target/Specificity	This DDIT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-149 amino acids from the C-terminal region of human DDIT3.
NCBI Accession	NP_001181982.1; NP_001181983.1; NP_001181984.1; NP_001181986.1; NP_004074.2

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Menge: 80 ul

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