Bio Background |
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex. |
Bio References |
Halls, M.L., et al. EMBO J. 29(16):2772-2787(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Need, A.C., et al. Eur. J. Hum. Genet. 17(7):946-957(2009) Uhl, G.R., et al. Arch. Gen. Psychiatry 65(6):683-693(2008) Sunahara, R.K., et al. Mol. Interv. 2(3):168-184(2002) |