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JAK2 Antibody (C-term)

JAK2 Antibody (C-term)

ArtNr	ABC-AP1125b-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, FC, IF
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	JAK2, Tyrosine-protein kinase JAK2, Janus kinase 2, JAK-2
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Primary Accession	O60674
Antigen Type	Synthetic Peptide
Application	FC, WB, IF
Bio Background	This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
Bio References	Joos, S., et al., Int. J. Cancer 103(4):489-495 (2003). Leung, K.C., et al., Proc. Natl. Acad. Sci. U.S.A. 100(3):1016-1021 (2003). Saharinen, P., et al., J. Biol. Chem. 277(49):47954-47963 (2002). Giordanetto, F., et al., Protein Eng. 15(9):727-737 (2002). Deo, D.D., et al., J. Biol. Chem. 277(24):21237-21245 (2002).
Clonality	Polyclonal
Clone/Animal Names	RB02956
Gene ID	3717
Gene Name	JAK2 (HGNC:6192)
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Confocal immunofluorescent analysis of JAK2 Antibody (C-term) (Cat#AP1125b) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	The anti-JAK2 Pab (Cat. #AP1125b) is used in Western blot to detect JAK2 in mouse thymus tissue lysate.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	JAK2 Antibody (C-term) (Cat. #AP1125b) flow cytometric analysis of K562 cells (right histogram) compared to a negative control (PBS alone) (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	130674
Antigen Region	1101-1132
Antigen Source	HUMAN
Target/Specificity	This JAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1101-1132 amino acids from the C-terminal region of human JAK2.
NCBI Accession	NP_004963.1

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ABC-AP1125b-ev-datasheet.pdf

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Menge: 80 ul

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Lieferung vsl. bis 04.10.2024

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