INHBB Antibody (C-term)

Synthetic Peptide

The inhibin beta B subunit joins the alpha subunit to
form a pituitary FSH secretion inhibitor. Inhibin has been shown
to regulate gonadal stromal cell proliferation negatively and to
have tumour-suppressor activity. In addition, serum levels of
inhibin have been shown to reflect the size of granulosa-cell
tumors and can therefore be used as a marker for primary as well as
recurrent disease. Because expression in gonadal and various
extragonadal tissues may vary severalfold in a tissue-specific
fashion, it is proposed that inhibin may be both a
growth/differentiation factor and a hormone. Furthermore, the beta
B subunit forms a homodimer, activin B, and also joins with the
beta A subunit to form a heterodimer, activin AB, both of which
stimulate FSH secretion.

Polyclonal

3625

Affinity Purified Rabbit Polyclonal Antibody (Pab)

All lanes : Anti-INHBB Antibody (C-term at 1:4000 dilution
Lane 1: A549 whole cell lysate
Lane 2: PC-3 whole cell lysate
Lane 3: Mouse testis lysate


Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 45 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

1:4000

WB

Anti-INHBB Antibody (C-term) at 1:2000 dilution + Mouse uterus lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 45 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

1:2000

IHC-P

P17491; P04088; Q04999; P27093; P42917; NP_002184.2

Rabbit Ig

369-397

This INHBB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 369-397 amino acids from the C-terminal region of human INHBB.