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ICAM2 Antibody (Center)

ICAM2 Antibody (Center)

ArtNr	ABC-AP11047c-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, FC
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	ICAM-2, ICAM2, CD102, Intercellular adhesion molecule 2
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Primary Accession	P13598
Antigen Type	Synthetic Peptide
Application	WB, FC
Bio Background	The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.
Bio References	Han, S., et al. Hum. Immunol. 71(7):727-730(2010) Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010) Davila, S., et al. Genes Immun. 11(3):232-238(2010) Sato, H., et al. Biochim. Biophys. Acta 1790(10):1198-1205(2009) Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 18(5):1651-1658(2009)
Clonality	Polyclonal
Clone/Animal Names	RB28558
Gene ID	3384
Gene Name	ICAM2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	ICAM2 Antibody (Center) (Cat. #AP11047c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ICAM2 antibody detected the ICAM2 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	ICAM2 Antibody (Center) (Cat. #AP11047c) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 2	FC
Dilution image 2	1:10~50
Other Accession	NP_000864.2; NP_001093256.1
Isotype	Rabbit Ig
Calculated MW	30654
Antigen Region	191-218
Antigen Source	HUMAN
Target/Specificity	This ICAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-218 amino acids from the Central region of human ICAM2.
NCBI Accession	NP_000864.2; NP_001093256.1; NP_001093257.1; NP_001093258.1; NP_001093259.1

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Menge: 80 ul

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