ArtNr |
ABC-AP10722a-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB, FC, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
GPAA1, GAA1, hGAA1, GAA1 protein homolog, Glycosylphosphatidylinositol anchor attachment 1 protein, Glycosylphosphatidylinositol anchor attachment 1 protein, Glycosylphosphatidylinositol anchor attachment 1 protein, GPI anchor attachment protein 1, GPI anchor attachment protein 1, GPI anchor attachment protein 1 |
Lieferbar |
|
Primary Accession |
O43292 |
Antigen Type |
Synthetic Peptide |
Application |
FC, IHC-P, WB |
Bio Background |
Posttranslational glycosylphosphatidylinositol (GPI)anchor attachment serves as a general mechanism for linkingproteins to the cell surface membrane. The protein encoded by thisgene presumably functions in GPI anchoring at the GPI transferstep. The mRNA transcript is ubiquitously expressed in both fetaland adult tissues. The anchor attachment protein 1 contains anN-terminal signal sequence, 1 cAMP- and cGMP-dependent proteinkinase phosphorylation site, 1 leucine zipper pattern, 2 potentialN-glycosylation sites, and 8 putative transmembrane domains. |
Bio References |
Jiang, W.W., et al. Mol. Cancer 6, 74 (2007) :Olsen, J.V., et al. Cell 127(3):635-648(2006)Ho, J.C., et al. Int. J. Cancer 119(6):1330-1337(2006)Vainauskas, S., et al. J. Biol. Chem. 280(16):16402-16409(2005)Vainauskas, S., et al. J. Biol. Chem. 279(8):6540-6545(2004) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB23990 |
Gene ID |
8733 |
Gene Name |
GPAA1 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
GPAA1 Antibody (N-term) (Cat. #AP10722a) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the GPAA1 antibody detected the GPAA1 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
GPAA1 antibody (N-term) (Cat. #AP10722a) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GPAA1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:50~100 |
Legend image 3 |
GPAA1 Antibody (N-term) (Cat. #AP10722a) flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Type image 3 |
FC |
Dilution image 3 |
1:10~50 |
Other Accession |
NP_003792.1 |
Isotype |
Rabbit Ig |
Calculated MW |
67623 |
Antigen Region |
46-73 |
Antigen Source |
HUMAN |
Target/Specificity |
This GPAA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-73 amino acids from the N-terminal region of human GPAA1. |
NCBI Accession |
NP_003792.1 |
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