MPP1 Antibody (Center)

NP_002427.1

This gene encodes the prototype of the membrane-associated
guanylate kinase (MAGUK) family proteins. MAGUKs interact with the
cytoskeleton and regulate cell proliferation, signaling pathways,
and intercellular junctions. The encoded protein is an extensively
palmitoylated membrane phosphoprotein containing a PDZ domain, a
Src homology 3 (SH3) motif, and a guanylate kinase domain. This
gene product interacts with various cytoskeletal proteins and cell
junctional proteins in different tissue and cell types, and may be
involved in the regulation of cell shape, hair cell development,
neural patterning of the retina, and apico-basal polarity and tumor
suppression pathways in non-erythroid cells. Multiple transcript
variants encoding different isoforms have been found for this gene.

4354

H

301-327

This MPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-327 amino acids from the Central region of human MPP1.