ArtNr |
ABC-AP1069a-ev |
Hersteller |
Abcepta
|
Menge |
80 ul |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Applikationen |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
USP21, USP23, Ubiquitin carboxyl-terminal hydrolase 21, Deubiquitinating enzyme 21, Ubiquitin thioesterase 21, Ubiquitin-specific-processing protease 21 |
Lieferbar |
|
Primary Accession |
Q9UK80 |
Antigen Type |
Synthetic Peptide |
Application |
IHC-P, WB |
Bio Background |
USP21 is a ubiquitin-specific protease, an enzyme that removes ubiquitin from ubiquitinated proteins. The encoded protein belongs to the C19 peptidase family, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. This protein has been reported to be capable of removing NEDD8 from NEDD8 conjugates. |
Bio References |
Puente, X.S., et al., Nat. Rev. Genet. 4(7):544-558 (2003).Gong, L., et al., J. Biol. Chem. 275(19):14212-14216 (2000).Hillier, L.D., et al., Genome Res. 6(9):807-828 (1996).Smith, T.S., et al., Biochim. Biophys. Acta 1490 (1-2), 184-188 (2000). |
Clonality |
Polyclonal |
Clone/Animal Names |
RB2809 |
Gene ID |
27005 |
Gene Name |
USP21 |
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
All lanes : Anti-hUSP21-M1 at 1:2000 dilutionLane 1: Hela whole cell lysateLane 2: T47D whole cell lysateLysates/proteins at 20 µg per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 63 kDaBlocking/Dilution buffer: 5% NFDM/TBST. |
Type image 1 |
WB |
Dilution image 1 |
1:2000 |
Legend image 2 |
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:50~100 |
Other Accession |
B2GUX4; Q9QZL6; Q2KJ72 |
Predicted |
B, M, Rat |
Isotype |
Rabbit Ig |
Calculated MW |
62656 |
Antigen Region |
1-30 |
Antigen Source |
HUMAN |
Target/Specificity |
This USP21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human USP21. |
NCBI Accession |
NP_001014443.1; NP_036607.3 |
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