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TIMP4 Antibody (Center)

TIMP4 Antibody (Center)

ArtNr	ABC-AP10148c-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	TIMP-4, TIMP4, Tissue inhibitor of metalloproteinases 4, Metalloproteinase inhibitor 4
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Primary Accession	Q99727
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.
Bio References	Nalpas, B., et al. Gut 59(8):1120-1126(2010) Bailey, S.D., et al. Diabetes Care (2010) In press : Wojciechowski, R., et al. Invest. Ophthalmol. Vis. Sci. (2010) In press : Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Liss, M., et al. Am. J. Pathol. 175(3):940-946(2009)
Clonality	Polyclonal
Clone/Animal Names	RB22433
Gene ID	7079
Gene Name	TIMP4
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	TIMP4 Antibody (Center) (Cat. #AP10148c) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the TIMP4 antibody detected the TIMP4 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	TIMP4 Antibody (Center) (Cat. #AP10148c) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the TIMP4 antibody detected the TIMP4 protein (arrow).
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	TIMP4 Antibody (Center) (Cat. #AP10148c) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TIMP4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:50~100
Other Accession	NP_003247.1
Isotype	Rabbit Ig
Calculated MW	25503
Antigen Region	48-74
Antigen Source	HUMAN
Target/Specificity	This TIMP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-74 amino acids from the Central region of human TIMP4.
NCBI Accession	NP_003247.1

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