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Mouse Monoclonal Antibody to TLR9

Mouse Monoclonal Antibody to TLR9

ArtNr	ABC-AO2370a
Hersteller	Abcepta
Menge	0.1mg
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Applikationen	WB, FC, IHC, ICC, ELISA
Clon	1B12H2
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CD289
Lieferbar
Primary Accession	Q9NR96
Application	WB, IHC, FC, ICC, E
Bio References	1.J Virol. 2015 Nov; 89(22):11396-405. ; 2.Immunogenetics. 2014 Dec; 66(12):675-81.;
Clonality	Monoclonal
Gene ID	54106
Gene Name	TLR9
Subtitle	Purified Mouse Monoclonal Antibody
Reactivity	H
Legend image 1	Black line: Control Antigen (100 ng); Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Type image 1	E
Legend image 2	Western blot analysis using TLR9 mAb against human TLR9 (AA: 868-1016) recombinant protein. (Expected MW is 43.4 kDa)
Type image 2	WB
Legend image 3	Western blot analysis using TLR9 mAb against HEK293 (1) and TLR9 (AA: 868-1016)-hIgGFc transfected HEK293 (2) cell lysate.
Type image 3	WB
Legend image 4	Flow cytometric analysis of A549 cells using TLR9 mouse mAb (green) and negative control (red).
Type image 4	FC
Legend image 5	Immunofluorescence analysis of SK-OV-3 cells using TLR9 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher
Type image 5	ICC
Legend image 6	Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using TLR9 mouse mAb with DAB staining.
Type image 6	IHC
Legend image 7	Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues using TLR9 mouse mAb with DAB staining.
Type image 7	IHC
Isotype	Mouse IgG2a
Calculated MW	115860
Formulation	Purified antibody in PBS with 0.05% sodium azide
Description	The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.;
	Clone: 1B12H2
Immunogen	Purified recombinant fragment of human TLR9 (AA: 868-1016) expressed in E. Coli.

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ABC-AO2370a-datasheet.pdf

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