ArtNr |
ABC-AO2318a |
Hersteller |
Abcepta
|
Menge |
100 ul |
Kategorie |
|
Typ |
Antibody Primary |
Applikationen |
WB, FC, IHC, ELISA |
Clon |
6B3E10 |
Specific against |
other |
Host |
Mouse |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
53BP1, TP53BP1, p53BP1, Tumor suppressor p53-binding protein 1, p53-binding protein 1 |
Lieferbar |
|
Primary Accession |
Q12888 |
Application |
WB, IHC, FC, E |
Bio References |
1. Cancer Res. 2012 Oct 1; 72(19):4974-83. 2. Int J Biochem Cell Biol. 2012 Sep; 44(9):1398-409. |
Clonality |
Monoclonal |
Gene ID |
7158 |
Gene Name |
|
Subtitle |
Purified Mouse Monoclonal Antibody |
Reactivity |
H |
Legend image 1 |
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng); |
Type image 1 |
E |
Dilution image 1 |
1/10000 |
Legend image 2 |
Figure 1: Western blot analysis using TP53BP1 mAb against human TP53BP1 recombinant protein. (Expected MW is 47.6 kDa) |
Type image 2 |
WB |
Dilution image 2 |
1/500 - 1/2000 |
Legend image 3 |
Figure 2: Western blot analysis using TP53BP1 mAb against HEK293 (1) and TP53BP1 (AA: 574-773)-hIgGFc transfected HEK293 (2) cell lysate. |
Type image 3 |
WB |
Dilution image 3 |
1/500 - 1/2000 |
Legend image 4 |
Figure 3: Flow cytometric analysis of HepG2 cells using TP53BP1 mouse mAb (green) and negative control (purple). |
Type image 4 |
FC |
Dilution image 4 |
1/200 - 1/400 |
Legend image 5 |
Figure 4: Immunohistochemical analysis of paraffin-embedded colon cancer tissues using TP53BP1 mouse mAb with DAB staining. |
Type image 5 |
IHC |
Dilution image 5 |
1/200 - 1/400 |
Legend image 6 |
Figure 5: Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues using TP53BP1 mouse mAb with DAB staining. |
Type image 6 |
IHC |
Dilution image 6 |
1/200 - 1/1000 |
Isotype |
IgG1 |
Calculated MW |
213574 |
Formulation |
Purified antibody in PBS with 0.05% sodium azide |
Description |
T protein p53 binding protein 1 may have a role in checkpoint signaling during mitosis, enhance TP53-mediated transcriptional activation and play a role in the response to DNA damage. |
|
Clone: 6B3E10 |
Immunogen |
Purified recombinant fragment of human TP53BP1 (AA: 574-773) expressed in E. Coli. |
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