BMP4 Antibody

WB, ICC, E

Monoclonal

BMP4

H, Rat

E

Figure 2:Western blot analysis using BMP4 mAb against human BMP4 (AA: 277-408) recombinant protein. (Expected MW is 41 kDa)

1/500 - 1/2000

WB

Figure 4:Western blot analysis using BMP4 mouse mAb against A549 (1) and C6 (2) cell lysate.

1/500 - 1/2000

IF

Figure 6:Immunofluorescence analysis of Hela cells using BMP4 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

1/100 - 1/500

46555

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Purified recombinant fragment of human BMP4 (AA: 277-408) expressed in E. Coli.